Kev tiv thaiv kev kub ntxhov rau cov nqaij qaib

• Thaum tshav kub kub hawb pob: tsim nyog cov cua kub hnyiab tuaj yeem ua rau kom lub cev kub hnyiab tau, tab sis kev hawb pob ntau dhau yuav ua rau CO2 excretion ntau dhau, CO2 ib feem ntawm cov ntshav yuav poob, pH tus nqi yuav nce, thiab alkalosis yuav induced; Central inhibition, ntau dhau ntawm H2CO3 hauv lub cev tuaj yeem ua rau acidosis.

• Lub plawv dhia ceev: cov pa oxygen tsis txaus hauv cov ntshav vim kev ntxhov siab thiab kub hnyiab (ua pa qis); Lub plawv dhia ceev ceev ua raws li lub plawv tsis ua hauj lwm, uas tuaj yeem ua rau venous rov qab mob, pulmonary ntshav stasis, edema, hypoxia thiab acidosis.

• Cov txheej txheem oxidation nyob rau hauv lub cev yog intensified: lub cev kub nce, oxidative metabolism ntawm peb yam tseem ceeb nyob rau hauv lub cev muaj zog, lub teeb meem metabolic intermediates thiab cov khoom kawg (endotoxins) nce, cell lipid membrane puas los ntawm oxidation, Qhov sib txawv ntawm phab ntsa ntawm cov hlab ntsha yog qhov loj, thiab nws yooj yim heev rau ua rau hemorrhage, hemolysis, cov ntaub so ntswg puas thiab autotoxicity. Nyob rau hauv lub xeev ntawm kev kub ntxhov, lub cev redox tsis txaus, thiab cov tsub zuj zuj ntawm endogenously generated dawb radicals (tsuas yog ROS) ua rau oxidative kev nyuaj siab. Nyob rau hauv lub xeev ntawm oxidative kev nyuaj siab, kev ua haujlwm ntawm endoplasmic reticulum yog hloov, ua rau endoplasmic reticulum kev nyuaj siab.

• Kev tso zis ntau ntxiv ntawm adrenal cortex cov tshuaj hormones: nyob rau hauv thawj theem, metabolism yog txhim kho, lub zog thiab protein noj yog nce, thiab lub cev nyob rau hauv lub xeev ntawm siab nro. Tom qab ntawd, qhov tso tawm ntawm thyroxine thiab cortisol (tiv thaiv kev ntxhov siab) txo qis, maj mam tso tawm, thiab tuaj yeem ua rau lymphocyte nucleic acid. Dicer kev ua si yog nce, cellular tiv thaiv thiab humoral tiv thaiv tsis muaj zog; paj hlwb excitability yog nce los yog inhibited, thiab lwm yam.

• Thaum tshav kub kub kev ntxhov siab txo qhov kev qhia ntawm cov kua tsib acid synthase thiab cov kua tsib acid hloov pauv cov enzymes tseem ceeb hauv daim siab, thiab cuam tshuam rau kev tso tawm thiab tso tawm ntawm cov kua tsib acid. Txo cov ntsiab lus ntawm FXR thiab TGR5 hauv daim siab yog qhov zoo rau kev sib txuas ntawm TG thiab cov roj deposition, ua rau muaj roj sib txawv.

• Kev tshem tawm ntau dhau ntawm cov quav thiab tso zis thiab cov quav dej: ua rau poob ntawm cov poov tshuaj, sodium thiab ntau yam kab hauv lub cev, qhov tsis txaus ntawm electrolyte tshuav thiab lub cev qhuav dej.

Kev ntsuas kom txo tau qhov kub ntxhov

Kev txo qis kev ntxhov siab yuav tsum tau kho kom zoo los ntawm ntau qhov ntev, uas tsis tuaj yeem daws tau los ntawm ib qho kev daws teeb meem.

1. Ua ntej, kho hom kev pub mis raws li cov txheej txheem ntau lawm thiab cov kev xav tau ntawm cov qaib (cov pob kws tau hloov dua siab tshiab rau hauv ntau hom qoob loo); siv cov kev ntsuas los txo kev ntxhov siab (xws li kev tswj qhov kub thiab txias, kev noj qab haus huv); Kev tswj kev huv huv (xws li plua plav, cov nqaij qaib huv si Siv cov tshuaj mycotoxin adsorbents thiab detoxifiers kom tshem tawm endotoxins (bile acids); muab kev tiv thaiv kab mob los ntawm kev tsim cov additives; tiv thaiv lub siab thiab ntxiv dag zog rau daim siab, txhim kho plab hnyuv permeability; txo lossis tshem tawm cov tshuaj tua kab mob subclinical siv. .

2. Muab qhov cua kom tsim nyog raws li tus naj npawb ntawm qaib hauv tsev qaib; kho cov kiv cua txoj hauj lwm, optimize cua ceev, thiab txhawb cov cua ncig; txo qhov ntim ceev; ua ib txoj haujlwm zoo ntawm cov khoom siv rwb thaiv tsev hauv tsev kom tsis txhob muaj hnub ci cua sov; siv cov evaporative txias ncoo los yog atomizing nozzles; Tswj dej thiab electrolyte tshuav, ntxiv cov vitamins; siv cov nroj tsuag rho tawm, cov roj tseem ceeb pub additives los daws thiab txo cov teebmeem ntawm kev kub ntxhov.

3. Feem ntau siv cov tshuaj tiv thaiv kev ntxhov siab, "kho cov tsos mob tab sis tsis yog lub hauv paus ua rau"

① Ntxiv cov electrolytes xws li sodium bicarbonate, ammonium chloride, potassium chloride, thiab lwm yam kom txo tau cov acidosis thiab tswj cov electrolyte tshuav.

② Ntxiv cov vitamins (xws li vitamin C, thiab E), thiab kab kawm (zinc, selenium, chromium) los txhim kho lub peev xwm antioxidant.

③Ntxiv cov tshuaj suav tshuaj ntsuab, rho tawm, roj yam tseem ceeb, amino acids, organic acids, thiab lwm yam.

4. Ntxiv cov kua tsib kua qaub los txo cov kev ntxhov siab thaum tshav kub kub thiab tswj hwm endoplasmic reticulum oxidative kev nyuaj siab

① Nyob rau hauv ib puag ncig kev ntxhov siab, ntxiv cov kua tsib kua qaub tuaj yeem txhim kho kev siv roj, txo lub cev kub nce, thiab txo qhov kub ntxhov.

② Nyob rau hauv ib puag ncig kev ntxhov siab, txo cov protein ntau, nce qib amino acid (tshwj xeeb tshaj yog methionine), ntxiv cov kua tsib acid, txhim kho cov protein siv tus nqi, thiab txo lub cev lub cev los ntawm kev kub ntxhov.

③Bile acids ntxiv rau cov khoom noj kom sib xyaw thiab tso tawm endotoxins, ua kom cov metabolism hauv mycotoxins, txo oxidative stressors, thiab txo oxidative kev nyuaj siab nyob rau hauv endoplasmic reticulum.

④ Ntxiv cov kua tsib kua qaub rau noj tuaj yeem ua rau muaj kev ua haujlwm ntawm cov enzymes antioxidant (SOD, GPH-x), txo cov ntsiab lus ntawm malondialdehyde (MDA), nce qib ntawm antioxidant (TAOC), thiab txo qhov kub ntxhov.

Xaus

Hauv ib lo lus, txhawm rau txo qhov kub ntxhov ntawm cov nqaij qaib, ua ntej ntawm tag nrho cov, nws yog ib qho tsim nyog los txhim kho ib puag ncig thiab txiav tawm cov kev ntxhov siab ib puag ncig kom ntau li ntau tau; Thib ob, txhawm rau txhim kho digestibility ntawm pub thiab txo lub nra ntawm cov hnyuv; tshem tawm cov co toxins dua los txo cov oxidative stressors; Thaum kawg, txhawm rau txhim kho lub cev muaj peev xwm antioxidant thiab txo qis Endoplasmic reticulum kev nyuaj siab relieves qhov tsis zoo physiological kev ua tau zoo los ntawm kev kub ntxhov thiab ua kom cov nqaij qaib ua tau zoo li qub.